Scientists explore the role of metabolism in immune response

Fan Lab

Scientists explore the role of metabolism in immune response

The immune system is one of the body’s most important defenders, a bodyguard protecting against infection and disease. As the development of immunotherapies to treat diseases, particularly in cancer treatments, continues to grow, so does the need to better understand the complexities of this system.

A team of metabolism researchers, led by Morgridge Institute investigator Jing Fan, is working to better understand the role of metabolism in immune response. In a paper published online in Nature Metabolism, the Fan Lab highlights how changing metabolism can regulate the different functional states in macrophages over the course of an immune response.